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500-KDA HD1 PROTEIN
Descriptors Found:
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DeCS
Descriptor
English
:
Plectin
Descriptor
Spanish
:
Plectina
Descriptor
Portuguese
:
Plectina
Synonyms
English
:
500 kDa HD1 Protein
500-kDa HD1 Protein
HD1 Protein, 500-kDa
HD1, Hemidesmosomal Protein
Hemidesmosomal Protein HD1
Tree Number:
D12.776.220.790.750
D12.776.744.736
Definition
English
:
A cytoskeletal linker protein with a
molecular weight
of greater than 500 kDa. It binds
INTERMEDIATE FILAMENTS
;
MICROTUBULES
; and
ACTIN CYTOSKELETON
and plays a central role in the organization and stability of the
CYTOSKELETON
.
Plectin
is phosphorylated by
CALMODULIN
KINASE; PROTEIN KINASE A; and
PROTEIN KINASE C.
History Note
English
:
2006(1982)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50941
Unique Identifier:
D051190
Occurrence in VHL
:
Similar:
DeCS